A review of in vitro methods to predict the clinical significance of red blood cell alloantibodies

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 34 , ISSUE 1 (March 2018) > List of articles

A review of in vitro methods to predict the clinical significance of red blood cell alloantibodies

Sandra J. Nance *

Keywords : RBC alloantibodies, clinical significance, ISBT Academy Day

Citation Information : Immunohematology. Volume 34, Issue 1, Pages 11-15, DOI: https://doi.org/10.21307/immunohematology-2018-004

License : (Transfer of Copyright)

Published Online: 16-October-2019

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ABSTRACT

This review was derived from a presentation made on September 2, 2016, for the first Academy Day presented by the Working Party on Immunohematology at the International Society of Blood Transfusion (ISBT) Congress in Dubai. The focus of this review is on the clinical significance of alloimmunization in transfusion—specifically, the parameters that contribute to a clinically significant alloantibody. The areas of focus were as follows: Introduction, Technical Aspects, and Indications and Limitations. Each section contains a brief review of selected literature and experiential knowledge. Case reports are needed to collect data on current outcomes of incompatible transfusion. The ISBT Working Party on Rare Donors has developed a form to capture case-specific information.

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