An overview of the Progenika ID CORE XT: an automated genotyping platform based on a fluidic microarray system

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 31 , ISSUE 2 (June 2015) > List of articles

An overview of the Progenika ID CORE XT: an automated genotyping platform based on a fluidic microarray system

Mindy Goldman * / Núria Nogués / Lilian M. Castilho

Keywords : blood group, DNA-based typing methodology, genotyping

Citation Information : Immunohematology. Volume 31, Issue 2, Pages 62-68, DOI: https://doi.org/10.21307/immunohematology-2019-072

License : (Transfer of Copyright)

Published Online: 26-October-2019

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ABSTRACT

Automated testing platforms facilitate the introduction of red cell genotyping of patients and blood donors. Fluidic microarray systems, such as Luminex XMAP (Austin, TX), are used in many clinical applications, including HLA and HPA typing. The Progenika ID CORE XT (Progenika Biopharma-Grifols, Bizkaia, Spain) uses this platform to analyze 29 polymorphisms determining 37 antigens in 10 blood group systems. Once DNA has been extracted, processing time is approximately 4 hours. The system is highly automated and includes integrated analysis software that produces a file and a report with genotype and predicted phenotype results.

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