American National Red Cross
Subject: Medical Laboratory Technology
ISSN: 0894-203X
eISSN: 1930-3955
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George Garratty / Patricia A. Arndt
Keywords : drugs, immune hemolytic anemia, autoantibody, drug-dependent antibody, nonimmunologic protein adsorption
Citation Information : Immunohematology. Volume 30, Issue 2, Pages 66-79, DOI: https://doi.org/10.21307/immunohematology-2019-100
License : (Transfer of Copyright)
Published Online: 06-November-2019
This review updates new findings in drug-induced immunehemolytic anemia (DIIHA) since the 2007 review in Immunohematology by these authors. Twelve additional drugs
have been added to the three tables listing drugs associated with drug-dependent antibodies, drugs associated with drug-independent antibodies, and drugs associated with nonimmunologic protein adsorption. Other updated findings include (1) piperacillin is currently the most commonly encountered cause of DIIHA, (2) new data on blood group specificity of drug-dependent antibodies, (3) drug-dependent antibodies detected in healthy donors, (4) DIIHA associated with transplantation, and (5) DIIHA associated with chemotherapeutic drugs.