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Citation Information : Immunohematology. Volume 6, Issue 1, Pages 9-11, DOI: https://doi.org/10.21307/immunohematology-2019-1031
License : (Transfer of Copyright)
Published Online: 20-December-2020
The authors studied an example of red cell anti-JMH (John Milton Hagen) that exhibited several characteristics of a possible clinically significant antibody able to cause red cell destruction in vivo. Strong serological reactivity, a positive monocyte monolayer assay, and immunoglobulin subclass determination as IgG3 all indicate possible ability to destroy red cells. A 51Cr-labeled red cell survival study was not done as the patient did not require red cell transfusions but may be recommended for this patient if transfusions become necessary.