Autoimmune hemolytic anemia and a further example of autoanti-Kpb

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 21 , ISSUE 3 (September 2005) > List of articles

Autoimmune hemolytic anemia and a further example of autoanti-Kpb

Edmond Lee / Gordon Burgess / Nay Win

Keywords : autoimmune hemolytic anemia, anti-Kpb

Citation Information : Immunohematology. Volume 21, Issue 3, Pages 119-121, DOI: https://doi.org/10.21307/immunohematology-2019-403

License : (Transfer of Copyright)

Published Online: 28-April-2020

ARTICLE

ABSTRACT

A 65-year-old Caucasian man with myelodysplasia was admitted with autoimmune hemolytic anemia and a Hb of 5.6 g/dL. The patient’s serum contained anti-K; the DAT on the patient’s RBCs reacted 3+ with anti-IgG and 3+ with anti-C3d.K– RBC units were transfused, but there was no sustained increase in Hb level. The samples were referred to the reference laboratory of the National Blood Service. The DAT results remained the same, with anti-K detected only in the serum. An eluate prepared from the patient’s DAT-positive RBCs revealed anti-Kpb specificity. This study reports an unusual case of autoanti-Kpb,which is different from previously published cases in that no free anti-Kpb was detectable in the serum.

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