The direct antiglobulin test in a hospital setting

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 19 , ISSUE 1 (March 2003) > List of articles

The direct antiglobulin test in a hospital setting

Joan Cid / Xavier Ortín / Víctor Beltran / Lourdes Escoda / Enric Contreras / Enric Elies / Carmen Martín-Vega

Keywords : DAT, hemolytic anemia, hemolysis

Citation Information : Immunohematology. Volume 19, Issue 1, Pages 16-18, DOI: https://doi.org/10.21307/immunohematology-2019-468

License : (Transfer of Copyright)

Published Online: 14-October-2020

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ABSTRACT

To evaluate the current use of the DAT in our hospital,we reviewed the charts of all patients who had a DAT performed in our laboratory. The collected data included DAT results and a previously completed laboratory evaluation of suspected hemolytic anemia. Four hundred sixty-three DATs were performed in our laboratory from April 1999 to October 2001.The DAT was negative in 434 (93.7%) cases and positive in 29 (6.3%) cases. A complete laboratory evaluation of suspected hemolytic anemia was seen in 179 (38.7%) cases. The incidence of a positive DAT was higher in the group of patients with > 2 signs of hemolysis (4/34 cases; 11.8%) than in the group of patients with ≤ 2 signs of hemolysis (5/145 cases;3.4%) (RR = 0.029;95% CI:0.08–1.03;p = 0.06). When a patient with anemia is being investigated, a complete laboratory evaluation for suspected hemolytic anemia should be done before performing a DAT.

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