Antibodies detected in samples from 21,730 pregnant women

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 19 , ISSUE 3 (September 2003) > List of articles

Antibodies detected in samples from 21,730 pregnant women

Snezana Jovanovic-Srzentic / Milan Djokic / Nenad Tijanic / Radmila Djordjevic / Nada Rizvan / Darko Plecas / Dejan Filimonovic

Keywords : non-anti-D antibodies, fetomaternal hemorrhage, screening, third trimester, pregnancy

Citation Information : Immunohematology. Volume 19, Issue 3, Pages 89-92, DOI: https://doi.org/10.21307/immunohematology-2019-484

License : (Transfer of Copyright)

Published Online: 14-October-2020

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ABSTRACT

Although anti-D is still the main cause of HDN, many other antibodies have been implicated. From September 1995 to April 2000,screening for RBC antibodies was performed on samples from 21,730 pregnant women regardless of RhD type. Standard tube and gel methods were used. Anti-D was identified in 254 samples;other antibody specificities were detected in 376 samples, for a total of 630 antibodies. For this study, 522 antibodies were considered clinically significant. The incidence of potentially clinically significant antibodies was 2.4 percent. The majority belonged to the Rh system, followed by anti-M, -Fya , -S, -Jka , and -Jkb . Among antibodies of no clinical significance, the most frequent were antiH, -Lea , and -P1.

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