Elimination of a requirement for Vel-negative red blood cells and successful transfusion following chromium-51 survival study

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Immunohematology

American National Red Cross

Subject: Medical Laboratory Technology

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ISSN: 0894-203X
eISSN: 1930-3955

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VOLUME 11 , ISSUE 2 (June 1995) > List of articles

Elimination of a requirement for Vel-negative red blood cells and successful transfusion following chromium-51 survival study

Richard J. Davey / Jo Lynn Procter

Citation Information : Immunohematology. Volume 11, Issue 2, Pages 39-42, DOI: https://doi.org/10.21307/immunohematology-2019-785

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Published Online: 17-November-2020

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ABSTRACT

A 42-year-old woman presented with anemia and complex serologic test results that included a requirement for Vel-negative red blood cells (RBCs). Rare Vel-negative units were located and transfused, but her anemia worsened. As further serologic evaluation was inconclusive, an in vivo recovery study with Vel-positive RBCs was performed. Normal 24-hour recovery of these cells resulted in removal of the Vel-negative antigen restriction and successful transfusion of the patient. Resolution of the inconclusive anti-Vel serology with an in vivo recovery study simplified the acquisition of blood for this patient and conserved rare RBC units.

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