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Citation Information : Immunohematology. Volume 9, Issue 4, Pages 101-104, DOI: https://doi.org/10.21307/immunohematology-2019-968
License : (Transfer of Copyright)
Published Online: 06-December-2020
The incidence of colorectal carcinoma was compared with the incidence of ABO and Lewis blood groups. The raw data showed the known overrepresentation of the Le(a-b) phenotype, but also suggested an association of colorectal carcinoma with the Le(a-b+) phenotype in group O individuals. When the data were adjusted by taking into account the known loss of Lewis antigens by Lewis-positive patients, this association could be shown to be statistically significant. These results may indicate involvement of the secretory H antigen in colorectal carcinoma.