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  • Immunohematology
  • Acta Neurobiologiae Experimentalis

 

Article | 18-October-2020

PEG-coated red blood cells - simplifying blood transfusion in the new millennium?

Timothy C. Fisher

Immunohematology, Volume 16 , ISSUE 1, 37–48

research-article | 30-November-2018

Isolation and characterization of human amniotic fluid and SH-SY5Y/BE(2)-M17 cell derived exosomes

Nayer Seyfizadeh, Narges Seyfizadeh, Reza Rahbarghazi, Alireza Nourazarian, Sajed Borzouisileh, Abdolhakim Palideh, Farideh Elahimanesh, Hamed Hamishehkar, Leyla Salimi, Mohammad Nouri, Maryam Abtin

Acta Neurobiologiae Experimentalis, Volume 79 , ISSUE 3, 262–270

Review | 26-October-2019

Kell and Kx blood group systems

The Kell and Kx blood group systems are expressed as covalently linked molecules on red blood cells (RBCs). The Kell blood group system is very polymorphic, with 35 antigens assigned to the system. The expression of Kell glycoprotein on RBCs is not critical to the erythrocyte function. However, the expression of Kx is critical to normal morphology, and null mutations are associated with the McLeod neuroacanthocytosis syndrome. The immunogenicity of the K antigen is second only to the D antigen

Gregory A. Denomme

Immunohematology, Volume 31 , ISSUE 1, 14–19

Case report | 26-October-2019

Weak D type 67 in four related Canadian blood donors

Correct donor D typing is critical to prevent recipient alloimmunization. No method can detect all variants, and the immunogenicity of many variants is unknown. Routine ABO and D serologic typings are performed in our laboratory by automated microplate testing. Until 2011, routine confirmation of D– status of first-time donors was performed by the manual tube indirect antiglobulin test (IAT); this was replaced by automated solidphase testing including weak D testing by IAT. Selected

Philip Berardi, Emma Bessette, Michiko Ng, Nancy Angus, Debra Lane, Lise Gariepy, Katerina Pavenski, Gorka Ochoa-Garay, Jacqueline Cote, Mindy Goldman

Immunohematology, Volume 31 , ISSUE 4, 159–162

Report | 16-October-2019

Rh and Kell blood group antigen prevalence in a multi-ethnic cohort in Nigeria: implications for local transfusion service

Antigens belonging to the Rh and Kell blood group systems are of major clinical significance because of their immunogenicity and the potential of their consequent antibodies to cause in vivo destruction of exogenous red blood cells (RBCs). Despite the widespread use of transfusion, there are sparse data on the prevalence of Rh and Kell system antigens and their ethnic variability in Nigeria. The objective of this study was to determine the prevalence of the five major Rh (D, C, c, E, e) and

Ademola Samson Adewoyin, Grace Ming Lee, Titilope Adenike Adeyemo, Omolade Augustina Awodu

Immunohematology, Volume 34 , ISSUE 2, 61–65

Report | 01-December-2019

Blood group antigen distribution in Lao blood donors

;), 3.04 percent C−, 2.39 percent e−, and 5.17 percent M−. The high prevalence of C, e, and Fya and immunogenicity of these antigens may induce alloimmunization in transfusion-dependent patients, creating difficulties providing blood from Lao donors. The information obtained from this study will be useful for improving transfusion therapy in the country, especially for estimation of the availability of compatible blood for patients who have produced antibodies.

Chirapha Keokhamphoui, Yupa Urwijitaroon, Douangchanh Kongphaly, Te Thammavong

Immunohematology, Volume 28 , ISSUE 4, 132–136

Article | 17-February-2021

A resource-conserving serologic and high-throughput molecular approach to screen for blood donors with an IN:−5 phenotype

in the state of Gujarat in western India. Because we originally observed the INRA– phenotype with the p.150His variant allele in a Muslim patient, it is conceivable that the trait is either restricted to the index case family or only common in the Muslim community to which the patient belongs. Further studies in the local subpopulations may provide more information on the frequency of the IN*02.–05 allele and the immunogenicity of IN:5 in transfusion recipients, if occurring among blood donors.

S.R. Joshi, S.B. Senjaliya, K. Srivastava, W.A. Flegel

Immunohematology, Volume 36 , ISSUE 4, 129–132

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