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  • Immunohematology


Article | 09-November-2020

Common variable immunodeficiency: diagnosis by absent ABO reverse type

Many causes for ABO discrepancy between red blood cell and serum testing have been cited in the literature. ABO discrepancy due to weak or absent reverse type is most often seen at the extremes of age. We report a case of ABO discrepancy in a 25-year-old woman who presented for wisdom teeth extraction. Initial serologic workup revealed total absence of isohemagglutinin anti-B in this group A, D+ individual. Further evaluation revealed decreased levels of all classes of immunoglobulins and a

Carmen J. Julius, Mindy Wade, Abdul Waheed, Donald L. McNeil, Melanie S. Kennedy

Immunohematology, Volume 13 , ISSUE 3, 80–83

Article | 17-November-2020

ABO discrepancy with monoclonal ABO reagents caused by a pH-dependent autoantibody

ABO discrepancy was noted when a patient’s unwashed saline red cell suspension was tested with monoclonal ABO reagents. The discrepancy was resolved when a washed (x 3) saline red cell suspension was used in repeat testing. The patient’s serum contained an autoagglutinin that reacted optimally below pH 7.0. The discrepancy occurred when monoclonal ABO reagents, formulated at a low pH, lowered the pH of the reaction mixture, and autoagglutination was observed.

Melanie S. Kennedy, Abdul Waheed, Jane Moore

Immunohematology, Volume 11 , ISSUE 3, 71–73

Case Study | 31-December-2020

A Case Study: An ABO Discrepancy Due to an Antibody to EDTA

Monica Tobar

Immunohematology, Volume 3 , ISSUE 3, 40–41

Case report | 01-December-2019

A case of masquerading alloantibodies:  the value of a multitechnique approach

Paula M.S. Wennersten, Laurie J. Sutor

Immunohematology, Volume 30 , ISSUE 3, 117–120

Review | 09-October-2019

Recognizing and resolving ABO discrepancies

Patient samples are routinely typed for ABO prior to transfusion. Determining the ABO group requires both red blood cell (RBC) antigen typing for A and B (forward type) and testing for anti-A and anti-B in the plasma (reverse type). An ABO discrepancy exists when the result of an ABO RBC typing, or forward type, does not agree with the result of the plasma typing, or reverse type. This brief review examines several causes of ABO discrepancies encountered in the clinical transfusion service

Geralyn M. Meny

Immunohematology, Volume 33 , ISSUE 2, 76–81

Article | 16-February-2021

Comparison of ABO genotyping methods: a study of two low-resolution polymerase chain reaction assays in a clinical testing laboratory

J.A. Keller, T. Horn, S. Scholz, S. Koenig, M.A. Keller

Immunohematology, Volume 35 , ISSUE 4, 149–153

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