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research-article | 30-November-2019

Detoxification-related gene expression accompanies anhydrobiosis in the foliar nematode (Aphelenchoides fragariae)

the expression of glutaredoxin and trehalose phosphate synthase genes (Fu et al., 2012). However, it is not entirely clear what other molecular mechanisms are involved in foliar nematode desiccation. Here, we report the de novo assembly of an A. fragariae transcriptome constructed from well-hydrated and 24-hr-desiccated nematodes. The most striking result was the wholesale upregulation of multiple genes encoding Phase I and II detoxification enzymes: numerous cytochrome p450s (CYPs), short chain

Zhen Fu, Paula Agudelo, Christina E. Wells

Journal of Nematology, Volume 52 , 1–12

Article | 10-June-2019


last step of penicillin G biosynthesis is located in peroxisomes where the PA is coupled to 6-aminopenicillanic acid. It suggests that the penicillin G biosynthesis is a cytosol detoxification process. It was also suggested that the large peroxisomes abundantly arranged at the periphery of the cytoplasm (Fig. 2C) seem to build a PA-barrier protecting the hyphal cells from the toxicity of the precursor of penicillin G biosynthesis [15, 16]. Based on electron microscopy and biochemical data, there

Wiesław Kurzątkowski, Paulina Górska, Małgorzata Główka, Katarzyna Woźnica, Aleksandra Zasada

Postępy Mikrobiologii - Advancements of Microbiology, Volume 58 , ISSUE 1, 80–85

Research Article | 21-May-2019


Heavy metals are found in all living organisms where, as indispensable microelements (e.g. zinc, iron, copper), are involved in endless metabolic processes. However, living organisms are also at a risk of exposure to highly toxic metals, including cadmium or lead, which do not play any physiological role. Among multiple mechanisms associated with the maintenance of micronutrient homeostasis and detoxification of unwanted metals, there is a family of low-molecular-weight, cysteine-rich proteins

Agnieszka Mierek-Adamska, Wioleta Tylman-Mojżeszek, Zuzanna Znajewska, Grażyna B. Dąbrowska

Postępy Mikrobiologii - Advancements of Microbiology, Volume 56 , ISSUE 2, 171–179

Short Communication | 15-March-2016

Enterobacter asburiae KUNi5, a Nickel Resistant Bacterium for Possible Bioremediation of Nickel Contaminated Sites

-carboxylate deaminase, indole-acetic acid and siderophore. It seems that KUNi5 could be a possible candidate for Ni detoxification and plant growth promotion in Ni-contaminated field.

Anirudha Paul, Samir Kumar Mukherjee

Polish Journal of Microbiology, Volume 65 , ISSUE 1, 115–118

Research Article | 21-May-2019


disrupting signal transduction. Thus, all organisms have developed multiple pathways for arsenic detoxification. In this article, we review recent advances in the understanding of arsenic toxicity and its transport routes in prokaryotes and eukaryotes, including a dual role of aquaglyceroporins in the uptake and efflux, active transport out of the cell via secondary ion pumps and sequestration of metalloid-thiol conjugates into vacuoles by primary ABC transporters. We believe that such studies are of

Seweryn Mucha, Mateusz Berezowski, Katarzyna Markowska

Postępy Mikrobiologii - Advancements of Microbiology, Volume 56 , ISSUE 1, 88–99

Review | 01-December-2019

The LAN blood group system: a review

phenotype), owing to several different molecular mechanisms affecting ABCB6: frameshift leading to a premature stop codon (deletion, insertion, or nonsense mutation of nucleotides); missense mutation; or intronic mutation responsible for RNA splicing defect. Despite the Lan antigen’s being reported to play a key role in erythropoiesis and detoxification of cells, Lan– people do not appear to demonstrate susceptibility to any disease or seemingly physiologic disorder. Anti-Lan has been

Thierry Peyrard

Immunohematology, Volume 29 , ISSUE 4, 131–135

Review | 04-May-2018

Developmental neurotoxicants and the vulnerable male brain: a systematic review of suspected neurotoxicants that disproportionally affect males

include: (1) greater glutathione availability in females; (2) greater sulfate-based detoxification capacity in females; (3) potentiating effects of co-exposure to neurotoxicants and testosterone; (4) greater neuroinflammatory response in males; (5) reduced vulnerability to oxidative stress in females; and (6) neuroprotective effects of female hormones (estrogen and progesterone), especially in the reduction of inflammation and oxidative stress.

Janet K. Kern, David A. Geier, Kristin G. Homme, Paul G. King, Geir Bjørklund, Salvatore Chirumbolo, Mark R. Geier

Acta Neurobiologiae Experimentalis, Volume 77 , ISSUE 4, 269–296

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