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  • Acta Neurobiologiae Experimentalis

 

research-paper | 30-November-2020

Estrogen receptor agonists induce anti-edema effects by altering α and β estrogen receptor gene expression

. We have shown previously that propyl pyrazole triol (PPT), as selective ESR1 agonist, and diarypropiolnitrile (DPN), as an ESR2 agonist, have a neuroprotective effect against TBI (Asl et al., 2013). First, the reduction in ESR1 and ESR2 expression after TBI and the inhibitory effect of E2 on this reduction were studied (Khaksari et al., 2015b). Secondly, the exact molecular signaling pathways that cause the neuroprotective function of ER agonists still remain, and the effects of these agonists on

Mohammad Khaksari, Zahra Hajializadeh, Saeed Esmaeili Mahani, Zahra Soltani, Gholamreza Asadikaram

Acta Neurobiologiae Experimentalis, Volume 81 , ISSUE 3, 286–294

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