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Article | 17-February-2021

Clinical impacts of DNA-based typing and provision of antigen-matched red blood cell units for chronically transfused patients with thalassemia

is inaccurate because of the contaminating donor erythrocytes in patient circulation. DNA-based typing is superior in situations of recent transfusions.8 Moreover, it can guide the antigen-matched transfusion in individual patients. Furthermore, autoantibodies are frequently found in patients with thalassemia, causing crossmatch problems.9 The prevalence of autoantibodies is 0.47–28.2 percent by direct antiglobulin test and 57.6 percent by flow cytometry depending on study population and

P. Watanaboonyongcharoen, S. Onspun, P. Rojnuckarin

Immunohematology, Volume 36 , ISSUE 4, 137–145

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