• Select Article Type
  • Abstract Supplements
  • Blood Group Review
  • Call to Arms
  • Hypothesis
  • In Memoriam
  • Interview
  • Introduction
  • Letter to the Editor
  • Short Report
  • abstract
  • Abstracts
  • Article
  • book-review
  • case-report
  • case-study
  • Clinical Practice
  • Commentary
  • Conference Presentation
  • conference-report
  • congress-report
  • Correction
  • critical-appraisal
  • Editorial
  • Editorial Comment
  • Erratum
  • Events
  • Letter
  • Letter to Editor
  • mini-review
  • minireview
  • News
  • non-scientific
  • Obituary
  • original-paper
  • original-report
  • Original Research
  • Pictorial Review
  • Position Paper
  • Practice Report
  • Preface
  • Preliminary report
  • Product Review
  • rapid-communication
  • Report
  • research-article
  • Research Communicate
  • research-paper
  • Research Report
  • Review
  • review -article
  • review-article
  • review-paper
  • Review Paper
  • Sampling Methods
  • Scientific Commentary
  • short-communication
  • short-report
  • Student Essay
  • Varia
  • Welome
  • Select Journal
  • Immunohematology


Report | 25-March-2020

From DNA to blood groups

Marion E. Reid

Immunohematology, Volume 24 , ISSUE 4, 166–169

Article | 06-December-2020

A possible relationship between colorectal carcinoma and ABO/Lewis blood groups

The incidence of colorectal carcinoma was compared with the incidence of ABO and Lewis blood groups. The raw data showed the known overrepresentation of the Le(a-b) phenotype, but also suggested an association of colorectal carcinoma with the Le(a-b+) phenotype in group O individuals. When the data were adjusted by taking into account the known loss of Lewis antigens by Lewis-positive patients, this association could be shown to be statistically significant. These results may indicate

Stephen M. Henry, D. Graeme Woodfiel

Immunohematology, Volume 9 , ISSUE 4, 101–104

Article | 01-April-2020

A novel study of association between Neisseria gonorrhoeae and the human carbohydrate blood groups

Previous studies of association of ABO blood groups with gonorrhea have shown contradictory results. Despite the interdependencies ofABO,Lewis,and secretor systems,none of the previous studies examined the combined effect of these systems on their proposed association with gonorrhea. This study attempted to redress that and used genotyping in addition to RBC phenotyping to determine correct tissue phenotypes. Samples from 131 gonorrhea-positive individuals and from 175 gonorrhea-negative

Holly E. Perry, Rick A. Franklin, Susan J. Bray, Min K. Lo, Lola A.C. Svensson, Stephen M. Henry

Immunohematology, Volume 23 , ISSUE 3, 100–104

Book Review | 14-October-2020

BOOK REVIEW: Human Blood Groups

Jill R. Storry

Immunohematology, Volume 18 , ISSUE 4, 123–123

Book Review | 10-November-2020

BOOK REVIEW: Human Blood Groups

Patrick L. Mollison

Immunohematology, Volume 12 , ISSUE 2, 92–93

Report | 09-October-2019

Distribution of blood groups in the Iranian general population

Ehsan Shahverdi, Mostafa Moghaddam, Ali Talebian, Hassan Abolghasemi

Immunohematology, Volume 32 , ISSUE 4, 135–139

Book Review | 09-October-2019

Bloody Brilliant: A History of Blood Groups and Blood Groupers

S. Gerald Sandler

Immunohematology, Volume 33 , ISSUE 2, 82–83

Article | 18-May-2020

The gene encoding the I blood group antigen: review of an I for an eye

Marion E. Reid

Immunohematology, Volume 20 , ISSUE 4, 249–252

Article | 26-October-2020

Terminology for red cell antigens - 1999 update

Geoff Daniels

Immunohematology, Volume 15 , ISSUE 3, 95–99

Article | 01-April-2020

Differences in ABO antibody levels among blood donors: a comparison between past and present Japanese,Laotian,and Thai populations

Toshio Mazda, Kenji Tadokoro, Ryuichi Yabe, Oytip NaThalang, Te Thammavong

Immunohematology, Volume 23 , ISSUE 1, 38–41

Article | 03-November-2020

The immunoglobulin molecule

Janet Sutherland

Immunohematology, Volume 14 , ISSUE 1, 12–18

Review | 01-December-2019

A review of the JR blood group system

Lilian Castilho, Marion E. Reid

Immunohematology, Volume 29 , ISSUE 2, 63–68

Report | 01-December-2019

Blood group antigen distribution in Lao blood donors

Chirapha Keokhamphoui, Yupa Urwijitaroon, Douangchanh Kongphaly, Te Thammavong

Immunohematology, Volume 28 , ISSUE 4, 132–136

Report | 16-March-2020

The polymorphism nt 76 in exon 2 of SC is more frequent in Whites than in Blacks

Akiko Fuchisawa, Christine Lomas-Francis, Kim Hue-Roye, Marion E. Reid

Immunohematology, Volume 25 , ISSUE 1, 18–19

Report | 25-March-2020

Molecular studies of DO alleles reveal that JO is more prevalent than HY in Brazil, whereas HY  is more prevalent in New York

Lilian Castilho, Wilson Baleotti, Edith Tossas, Kim Hue-Roye, Karina R. Ribeiro, Christine Lomas-Francis, Daisy Charles-Pierre, Marion E. Reid

Immunohematology, Volume 24 , ISSUE 4, 135–137

Article | 14-October-2020

Jk and Mi.III phenotype frequencies in North Vietnam

Nguyen Thi Huynh, Tran Thi Duyen, Mai Thanh Huong, Derek S. Ford

Immunohematology, Volume 19 , ISSUE 2, 57–58

Case report | 25-March-2020

RHD deletion in a patient with chronic myeloid leukemia

Ann Murdock, Deborah Assip, Kim Hue-Roye, Christine Lomas-Francis, Zong Hu, Sunitha Vege, Connie M. Westhoff, Marion E. Reid

Immunohematology, Volume 24 , ISSUE 4, 160–164

Article | 03-November-2020

GIL: a red cell antigen of very high frequency

Geoff Daniels, E. Nicole DeLong, Virginia Hare, Susan T. Johnson, Pierre-Yves LePennec, Delores Mallory, M. Jane Marshall, Cindy Oliver, Peggy Spruell

Immunohematology, Volume 14 , ISSUE 2, 49–52

Article | 26-October-2019

HEA BeadChipTM technology in immunohematology

Cinzia Paccapelo, Francesca Truglio, Maria Antonietta Villa, Nicoletta Revelli, Maurizio Marconi

Immunohematology, Volume 31 , ISSUE 2, 81–90

Report | 01-December-2019

Prevalence of RHD*DOL and RHCE*ce(818T)  in two populations

Christine Halter Hipsky, Daiane Cobianchi da Costa, Ricardo Omoto, Angela Zanette, Lilian Castilho, Marion E. Reid

Immunohematology, Volume 27 , ISSUE 2, 66–67

Article | 18-October-2020

PEG-coated red blood cells - simplifying blood transfusion in the new millennium?

Timothy C. Fisher

Immunohematology, Volume 16 , ISSUE 1, 37–48

Report | 01-December-2019

SC*994C>T causes the Scnull phenotype in Pacific Islanders and successful transfusion of Sc3+ blood to a patient with anti-Sc3  

Marion E. Reid, Kim Hue-Roye, Randall W. Velliquette, Kathleen Larimore, Sue Moscarelli, Nicolas Ohswaldt, Christine Lomas-Francis

Immunohematology, Volume 29 , ISSUE 2, 69–72

Report | 11-March-2020

The Indian blood group system

Qun Xu

Immunohematology, Volume 27 , ISSUE 3, 89–93

Report | 12-March-2020

RHCE*ceAR encodes a partial c (RH4) antigen

Marion E. Reid, Christine Halter Hipsky, Christine Lomas-Francis, Akiko Fuchisawa

Immunohematology, Volume 26 , ISSUE 2, 57–59

Case report | 13-April-2020

Case report: DNA testing resolves unusual serologic results in the Dombrock system

Diane MacFarland, Kim Hue-Roye, Scott Carter, Dawn Moreau, James Barry, Marilyn K. Moulds, Christine Lomas-Francis, Marion E. Reid

Immunohematology, Volume 22 , ISSUE 2, 69–71

Report | 16-October-2019

Method-specific and unexplained reactivity in automated solid-phase testing and their association with specific antibodies

Mary E. Harach, Joy M. Gould, Rosemary P. Brown, Tricia Sander, Jay H. Herman

Immunohematology, Volume 34 , ISSUE 3, 93–97

Report | 25-March-2020

The potential of blood group genotyping for transfusion medicine practice

Connie M. Westhoff

Immunohematology, Volume 24 , ISSUE 4, 190–195

Article | 01-April-2020

An alloantibody to a highprevalence MNS antigen in a person with a GP.JL/Mk phenotype

John Ratliff, Susan Veneman, Joan Ward, Christine Lomas-Francis, Kim Hue-Roye, Randall W. Velliquette, Laima Sausais, Twilla Maldonado, Janet Miyamoto, Yolanda Martin, David Slater, Marion E. Reid

Immunohematology, Volume 23 , ISSUE 4, 146–149

Report | 01-December-2019

Validation of a blood group genotyping method based on high-resolution melting curve analysis

The detection of polymorphism is the basis of blood group genotyping and phenotype prediction. Genotyping may be useful to determine blood groups when serologic results are unclear. The development and application of different methods for blood group genotyping may be needed as a substitute for blood group typing. The purpose of this study is to establish an approach for blood group genotyping based on a melting curve analysis of realtime polymerase chain reaction (PCR). Using DNA extracted

Tianxiang Gong, Ying Hong, Naihong Wang, Xuemei Fu, Changhua Zhou

Immunohematology, Volume 30 , ISSUE 4, 161–165

Article | 15-April-2020

Efficacy of murine monoclonal antibodies in RBC phenotyping of DAT-positive samples

Edmond Lee, Kevin Hart, Gordon Burgess, Gregory R. Halverson, Marion E. Reid

Immunohematology, Volume 22 , ISSUE 4, 161–165

case-report | 25-June-2021

Neonatal testing leading to the identification of Bh (para-Bombay) phenotype in the mother: case report with review of the literature

G. Mohan, A. Vaidya, S. Shastry

Immunohematology, Volume 37 , ISSUE 2, 59–63

Case report | 16-October-2019

Management of pregnancy sensitized with anti-Inb with monocyte monolayer assay and maternal blood donation

Raj Shree, Kimberly K. Ma, Lay See Er, Meghan Delaney

Immunohematology, Volume 34 , ISSUE 1, 7–10

Report | 25-March-2020

DNA-based assays for patient testing: their application, interpretation, and correlation of results

Christine Lomas-Francis, Helene DePalma

Immunohematology, Volume 24 , ISSUE 4, 180–190

Case report | 01-December-2019

Red blood cell phenotype matching for various ethnic groups

Karafa S.W. Badjie, Craig D. Tauscher, Camille M. van Buskirk, Clare Wong, Sarah M. Jenkins, Carin Y. Smith, James R. Stubbs

Immunohematology, Volume 27 , ISSUE 1, 12–19

Report | 12-March-2020

Application of real-time PCR and melting curve analysis in rapid Diego blood group genotyping

Marcia C. Zago Novaretti, Azulamara da Silva Ruiz, Pedro Enrique Dorlhiac-Llacer, Dalton Alencar Fisher Chamone

Immunohematology, Volume 26 , ISSUE 2, 66–70

Review | 20-March-2020


Geoff Daniels

Immunohematology, Volume 25 , ISSUE 4, 152–159

Report | 20-March-2020

Characterization of three novel monoclonal anti-Oka

Mary H. Tian, Gregory R. Halverson

Immunohematology, Volume 25 , ISSUE 4, 174–178

Review | 09-October-2019

The Augustine blood group system, 48 years in the making

Geoffrey Daniels

Immunohematology, Volume 32 , ISSUE 3, 100–103

Case report | 01-December-2019

Blood group genotyping in a multitrauma patient: a case report

Currently DNA-based analysis of blood groups is mainly used to improve transfusion safety by reducing alloantibody formation in multiply transfused patients and by monitoring pregnancies at risk for hemolytic disease of the fetus and newborn. We present a case in which genotyping was performed after massive transfusion with unmatched group O, D– blood in a trauma setting. Our patient was genotyped as O1A1 and predicted to be D–, and we therefore transfused group A, D– red

Joyce Curvers, Volkher Scharnhorst, Masja de Haas, Loes Warnier-Wandel, Daan van de Kerkhof

Immunohematology, Volume 28 , ISSUE 3, 85–87

Article | 16-October-2019

Low-ionic-strength saline solution–antiglobulin test (LISS-AGT)

suspended in LISS. Modifications of the method led to development of the commercially prepared LISS additive solutions in use today. The LISS-AGT can be used effectively to detect alloantibodies of all major blood groups in antibody detection, antibody identification, and crossmatching procedures.

LeeAnn Walker

Immunohematology, Volume 34 , ISSUE 2, 57–60

Review | 02-May-2020

Review: the Kell, Duffy, and Kidd blood group systems

After the discovery (over 50 years ago) that the IAT could be applied to the detection of antibodies to blood group antigens, there was a rapid increase in the identification of alloantibodies that caused transfusion reactions or HDN. After Rh, antibodies in the Kell, Duffy, and Kidd blood group systems were the next in clinically significant antibodies to be revealed. Much of what has been learned about these blood groups since the journal Immunohematology issued its first edition has to do

Constance M. Westhoff, Marion E. Reid

Immunohematology, Volume 20 , ISSUE 1, 37–49

Article | 10-April-2021

Comparative evaluation of the conventional tube test and column agglutination technology for ABO antibody titration in healthy individuals: a report from India

each person before blood donation. As per the institutional policy, anti-A/-B titration is routinely performed on samples from blood donor units at our blood center; the intent was to avoid hemolytic reactions caused by transfusion of non–group-specific platelet concentrates. Therefore, separate institutional review board approval was not obtained for this study. Thirty individuals, each of blood groups A, B, and O, were enrolled. Table 1 shows the characteristics of the enrolled individuals

S.S. Datta, S. Basu, M. Reddy, K. Gupta, S. Sinha

Immunohematology, Volume 37 , ISSUE 1, 25–32

Article | 16-November-2020

Rhmod phenotype: a parentage problem solved by denaturing gradient gel electrophoresis of genomic DNA

Initial Rh phenotyping of a man with hemolytic anemia, his wife, and son appeared to exclude paternity. No exclusion was found in other blood groups or in the human leukocyte antigen (HLA) system; excluding Rh, the paternity index was 98.58 percent. Samples from these three family members, and two other family members, were tested with additional Rh antisera. The results indicated that the propositus has an Rhmod phenotype with expression of c, weak e, and very weak D, E, and G antigens. To

Fiona J. Steers, Maura Wallace, Marialuisa Mora, Ben Carritt, Patricia Tippett, Geoff Daniels

Immunohematology, Volume 12 , ISSUE 4, 154–158

Article | 27-December-2020

An update on Rodgers and Chido, the antigenic determinants of human C4

Rodgers (Rg) and Chido (Ch) blood groups are antigenic determinants of the fourth component of human complement (C4). Nine determinants have been defined by means of hemagglutination-inhibition (HAI) with polyspecific human antiserums. The association of C4A isotypes with Rg and of C4B isotypes with Ch is strong hut not complete. Derived amino acid sequences from the C4d region of selected C4 allotypes of known antigenic expression have provided support for the previously reported complex

Carolyn M. Giles

Immunohematology, Volume 5 , ISSUE 1, 1–6

Article | 18-October-2020

Fyx is associated with two missense point mutations in its gene and can be detected by PCR–SSP

Christoph Gassner, Richard L. Kraus, Tadeja Dovc, Susanne Kilga-Nogler, Irene Utz, Thomas Mueller, Friedrich Schunter, Diether Schoenitzer

Immunohematology, Volume 16 , ISSUE 2, 61–67

Article | 14-October-2020

Acute hemolytic transfusion reaction caused by anti-Coa

Randal B. Covin, Karen S. Evans, Richard Olshock, Hannis W. Thompson

Immunohematology, Volume 17 , ISSUE 2, 45–49

Article | 26-October-2020

Serologic and molecular investigations of a chimera

serologic (HLA class I and red cell blood groups) typing techniques were employed to investigate a number of polymorphic loci located on different chromosomes. Chimerism was identified in 8 out of the 14 chromosomes tested: chromosome 1 (Duffy), 6 (HLA class I and II), 9 (ABO), 11 (HUMTH01), 12 (HUMPLA2A1), 15 (HUMFES/FPS), 18 (Kidd) and 21 (D21S11). The proposita was determined to be a probable dispermic chimera, based on the results of the serology and molecular studies.

Nicole A. Mifsud, Albert P. Haddad, Cathie F. Hart, Jennifer A. Condon, Michael Swain, Rosemary L. Sparrow

Immunohematology, Volume 15 , ISSUE 3, 100–104

Case report | 16-October-2019

A delayed and acute hemolytic transfusion reaction mediated by anti-c in a patient with variant RH alleles

The Rh system is the most complex of the human blood groups. Of the 55 antigens that have been characterized, the system’s principal antigens D, C, E, c, and e are responsible for the majority of clinically significant Rh antibodies. In the last few years, advancements in molecular testing have provided a wealth of information on the genetic diversity of the Rh locus. This case report describes a patient with variant RHD*DAR alleles inherited in conjunction with two compound heterozygote

Tiffany K. Walters, Thomas Lightfoot

Immunohematology, Volume 34 , ISSUE 3, 109–112

Review | 17-March-2020

The ABO blood group system revisited: a review and update

The antigens of the ABO system were the first to be recognized as blood groups and actually the first human genetic markers known. Their presence and the realization of naturally occurring antibodies to those antigens lacking from the cells made sense of the erratic failure of blood transfusion hitherto and opened up the possibility of a safe treatment practice in life-threatening blood loss. Although initially apparently simple, the ABO system has come to grow in complexity over the years. The

Jill R. Storry, Martin L. Olsson

Immunohematology, Volume 25 , ISSUE 2, 48–59

Review | 29-October-2019

Raph blood group system

This review describes the current state of knowledge of the Raph blood group system, which consists of a single antigen, MER2. MER2 was initially classified as a high-incidence antigen in the 901 series of blood groups, formerly known as 901011, but was reclassified as an antigen in the Raph blood group system in 2004. There have been six reports of human alloantibodies to MER2. Three of the subjects were found to have a stop codon in the CD151 gene, which encodes a member of the tetraspanin

Michele Hayes

Immunohematology, Volume 30 , ISSUE 1, 6–10

Report | 01-December-2019

Cryopreservation of red blood cell units with a modified method of glycerolization and deglycerolization with the ACP 215 device complies with American and European requirements

percent for AS3-preserved RBCs and 0.25 ± 0.08 percent for RBCs preserved with SAG-M. On expiration, 32 percent of initial ATP values were measured in AS3-preserved RBCs vs. 62 percent in SAG-M–preserved RBCs. This modified method of glycerolization and deglycerolization meets the quality requirements of the European Council and the AABB standards. The prolonged storage of thawed RBCs enables optimized transfusion management for patients with rare blood groups.

Jana List, Michaela Horvath, Gerda C. Leitner, Günter Weigel

Immunohematology, Volume 28 , ISSUE 2, 67–73

Report | 01-December-2019

Seroprevalence of unexpected red blood cell antibodies among pregnant women in Uganda

identification. Of the 1001 blood samples tested, 48.9 percent, 26.4 percent, 21.0 percent, and 3.8 percent tested positive for blood groups O, A, B, and AB, respectively. Of these samples, 23 (2.3%) were negative for D, and 55 (5.5%) showed initial reactivity with at least one screening RBC. The RBC antibody screen was repeated on these 55 samples, and antibody identification was performed at the Johns Hopkins Hospital Blood Bank in Baltimore, Maryland. Twenty-one of the 55 samples were confirmed to have

Kristina Eipl, Clemensia Nakabiito, Kabali Bwogi, Mahnaz Motevalli, Angela Roots, Lorraine Blagg, J. Brooks Jackson

Immunohematology, Volume 28 , ISSUE 4, 115–117

Article | 20-December-2020

Human leukocyte antigens (HLA) class I (Bg) on red cells studied with monoclonal antibodies

Monoclonal antibodies, capable of detecting monomorphic epitopes on HLA class I polypeptides and beta-microglobulin (ß2-M), have been used by a variety of techniques to ascertain the type of structure detected on red blood cells (RBCs). Hemagglutinatlon with class I monoclonal antibodies confirmed the reported relationship between Bg blood groups and HLA. It also established that the expression of HLA on RBCs which do not have nuclei is not normally strong, hut may be enhanced in patients

Carolyn M. Giles

Immunohematology, Volume 6 , ISSUE 3, 53–58

Report | 16-October-2019

Blood chimerism in twins

ögren syndrome, systemic lupus erythematosus, and systemic sclerosis. In addition to chimerism of ABO blood groups being possibly mistaken for ABO subgroups, these autoimmune diseases may affect other serologic immunohematologic tests. This study aimed to determine the frequency of chimerism in DTs through ABO and D testing using the tube method, column agglutination, and short tandem repeat (STR) assays. Among the 103 subjects assessed for this study, 24 subjects (12 pairs) were excluded

Letícia Tavares, Daiane Cobianchi da Costa, Anna Paula de Borba Batschauer, Luiz Fernando Job Jobim, Gisele Menezes Ewald, Carolina de Mello, Eduardo Samuel Alvarez Velazquez, Alexandre Geraldo

Immunohematology, Volume 34 , ISSUE 4, 151–157

Article | 13-April-2020

Rare blood donors: a personal approach

importance of the NBGRL in identifying rare blood groups and in providing and coordinating services and the importance of keeping in close contact with the rare donors to encourage and promote their donations, which may save lives.

Cyril Levene, Orna Asher, Eilat Shinar, Vered Yahalom

Immunohematology, Volume 22 , ISSUE 2, 64–68

Report | 16-March-2020

Transfusion of rare cryopreserved red blood cell units stored at -80°C: the French experience

no mandatory time restriction in France. The National Rare Blood Bank currently includes 962 (17.5%) RBC units aged 10 years or more and 153 (2.8%) aged 20 years or more. Since 1994, 1957 RBC units have been thawed and transfused, among which 118 were aged 10 years or more and 8 were aged 20 years or more. Discarding RBC units older than 10 years may be highly sensitive for very rare blood groups, e.g., U–, of which approximately 30 percent of the cryopreserved units are aged 10 years or

Thierry Peyrard, Bach-Nga Pham, Pierre-Yves Le Pennec, Philippe Rouger

Immunohematology, Volume 25 , ISSUE 1, 13–17

No Record Found..
Page Actions