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Case report | 01-December-2019

Hemolytic disease of the fetus and newborn owing to anti-U, successfully treated with repeated intrauterine transfusions

this report we present the use of a noninvasive method to detect anemia in the fetus and the subsequent use of intrauterine transfusion (IUT) with blood of a very rare phenotype. For the first time, we used deglycerolized and 3-week-old red blood cell units for IUT without signs of adverse reactions and with the expected effect on the hemoglobin value. We conclude that this transfusion strategy could be applied safely.

Johanna Strindberg, Joachim Lundahl, Gunilla Ajne

Immunohematology, Volume 29 , ISSUE 2, 51–54

Case report | 26-October-2019

Severe hemolytic disease of the fetus and newborn due to anti-C+G

Riina Jernman, Vedran Stefanovic, Anu Korhonen, Katri Haimila, Inna Sareneva, Kati Sulin, Malla Kuosmanen, Susanna Sainio

Immunohematology, Volume 31 , ISSUE 3, 123–127

Article | 15-April-2020

Update on HDFN: new information on long-standing controversies

from anti-D was a significant cause of perinatal mortality or long-term disability. Routine administration of RhIG to D– women during pregnancy and shortly after the birth of D+ infants effectively reduced the incidence of HDFN caused by anti-D. Maternal alloimmunization to other RBC antigens in the Rh, Kell, and other blood group systems can not be routinely prevented and these antibodies can also cause HDFN. Advances in prenatal care, noninvasive monitoring, and intrauterine transfusion

Anne F. Eder

Immunohematology, Volume 22 , ISSUE 4, 188–195

Article | 16-October-2019

Anti-Vel alloimmunization and severe hemolytic disease of the fetus and newborn

intrauterine transfusion later in gestation. The patient was able to donate 4 units; these were kept refrigerated for 3–5 days and then frozen at the local blood center. At 24 weeks of gestation, the MCA-PSV became elevated to 1.89 multiples of the median (MoM), and the patient was referred back to our Fetal Center (>1.5 MoM is indicative of severe fetal anemia8). A repeat MCA-PSV was 2.0 MoM, and the repeat maternal anti-Vel titer was 16. A decision was made to proceed with intrauterine transfusion

K.J. Moise, Y. Morales, M.F. Bertholf, S.N. Rossmann, Y. Bai

Immunohematology, Volume 33 , ISSUE 4, 152–154

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